The Wake Forest Institute for Regenerative Medicine (WFIRM) is the recipient of the inaugural U.S. National Science Foundation (NSF) Engines Program award. The NSF Engines: Piedmont Triad Regenerative Medicine Engine is a regional project to provide an innovation ecosystem to stimulate workforce development, job creation, and economic growth through the development of technologies that benefit the emerging regenerative medicine industry.

The NSF Engines: Piedmont Triad Regenerative Medicine Engine core team consists of WFIRM, North Carolina Agricultural and Technical State University (NC A&T), Winston Salem State University (WSSU), Forsyth Technical Community College, and RegenMed Development Organization (ReMDO). The team is supported by multiple businesses, governmental entities, and not-for-profit agencies, including Axiom Space, Epredia, Oracle, Piedmont Triad municipalities, Greater Winston-Salem Inc. Over 80 partners have joined the regional effort.