NSF Engines: Piedmont Triad Regenerative Medicine Engine

About the PTRME

Our Ecosystem and Mission 

At the heart of the Piedmont Triad Regenerative Medicine Engine lies the mission to translate use-inspired research to manufacturable regenerative medicine technologies. Developing accessible, effective, and scalable technologies are fundamental to achieving this goal, as they enhance consistency, reduce variability, and improve the quality of regenerative medicine products. 

Ecosystem Advancements 

Standardization: By reducing reliance on custom-made or variable components, these technologies enable uniformity across applications, fostering collaboration and innovation.

Scalability: Innovations like modular bioreactors and universal media support the industrial-scale manufacturing of tissues and cells, ensuring regenerative medicine technologies can reach more people. 

Sustainability: Animal-free and chemically defined solutions reduce ethical concerns and environmental impacts, aligning with global sustainability goals. 

Mission Alignment 

These advancements are pivotal in fulfilling our mission to lead the field by developing regenerative medicine technologies that not only push the boundaries of science but also create pathways for widespread adoption. By addressing critical bottlenecks in tissue engineering, we are building an ecosystem where breakthrough research translates into commercialization.  

The PTRME Leadership Team

Tim Bertram, Phd

Chief Executive Officer

Jesse Thornburg, PhD

Chief Operations Officer

Karen Barnes

Ecosystem Development Officer

Anthony Atala, MD

Chief Innovation Officer

Stefanie Walling, MBA

Chief Communications Officer

Jessica Jones

External Evaluator

Josh Hunsberger

Chief Partnership and Stakeholder Engagement Officer

Del L. Ruff

Regional Engagement Lead

North Carolina A&T State University

Jill Keith, PhD

Regional Engagement
Co-Lead

Winston-Salem State University

Brenda Latham-Sadler, MD

Regional Engagement
Co-Lead

Wake Forest University School of Medicine

Russ H. Read, MA

Workforce Development Co-Lead

National Center for the Biotechnology Workforce

Joan F. Schanck, MPA

Workforce Development Co-Lead

Wake Forest Institute for Regenerative Medicine

Graça Almeida-Porada, MD, PhD

Research & Development Co-Lead

Wake Forest Institute for Regenerative Medicine

Salil Desai, PhD

Research & Development Co-Lead

North Carolina A&T State University

Steven R. Bauer, PhD

Translational Lead

Bert Clayton, BS

Translation Co-Lead

Jana Stoudemire

In-Space Lead

Isaac Perry, MBA

Economic Development Officer

Innovation Quarter & Greater Winston-Salem, Inc

Tim Wright, MD

Entrepreneurial Officer

Julie Watson, JD

Legal / IP Officer

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Dr. Anthony Atala serves as the Director of Innovation for the NSF-PTRME and is the Founder and Director of the Wake Forest Institute for Regenerative Medicine. Dr. Atala is founding board member and equity holder in entities within the PTRME ecosystem, including Biorg, Caylyx, the Tygrus subsidiary Miracus, Plureon, and Precise Bio. He does not receive any compensation from these commercial entities.

Dr. Timothy A. Bertram serves as the CEO for the NSF-PTRME and is the Chief Economic Development Program Officer for the Wake Forest Institute for Regenerative Medicine. Dr. Bertram serves as Chair of the MasKidney Board of Directors and is founder of ProKidney. He is an equity holder in both entities which are within the PTRME ecosystem. Dr. Bertram does not receive any compensation from these commercial entities.

Dr. Shay Soker serves as an investigator under the NSF-PTRME grant and is a Professor at the Wake Forest Institute for Regenerative Medicine. He is a founding board member and equity holder in several entities within the PTRME ecosystem, including Biorg and Precise Bio. Dr. Soker does not receive any compensation from these commercial entities.

Timothy R. Wright is a member of the PTRME team leadership team and has an appointment at the Wake Forest Institute for Regenerative Medicine as Portfolio Director.  Mr. Wright is an equity holder, President and CEO of BIORG, a company within the PTRME ecosystem.  He does not receive any compensation from this commercial entity.

Dr. James Yoo serves as an investigator under the NSF-PTRME grant and is a Professor at the Wake Forest Institute for Regenerative Medicine. Dr. Yoo is a founding member and equity holder of Biorg, an entity within the PTRME ecosystem. He does not receive any compensation from this commercial entity.